دانلود مقالات ISI درباره [35S] GTPγS + ترجمه فارسی

The tamoxifen derivative ridaifen-B is a high affinity selective CB2 receptor inverse agonist exhibiting anti-inflammatory and anti-osteoclastogenic effects

Keywords: [35S] GTPγS; Cannabinoid receptors; G-protein coupled receptors; Inverse agonist; Antagonist; Drug action; AC; adenylyl cyclase; CB1R; cannabinoid receptor type 1; CB2R; cannabinoid receptor type 2; CHO; Chinese hamster ovary; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hy

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Induction of oxidative stress by long-term treatment of live HEK293 cells with therapeutic concentration of lithium is associated with down-regulation of δ-opioid receptor amount and function

Keywords: [35S] GTPγS; AAS; atomic absorption spectroscopy; Ab; antibody; BD; bipolar disorder; DADLE; (2-d-alanine-5-d-leucine)-enkephalin = Tyr-d-Ala-Gly-Phe-d-Leu; DCF; 2′,7′-dichlorofluorescein; DCFH-DA; 2′,7′-dichlorofluorescin diacetate (synonym dichlorodihydr

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2018 سفارش ترجمه

Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors

Keywords: [35S] GTPγS; 25D-NBOMe; 2-(2,5-dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine; 25E-NBOMe; 2-(4-ethyl-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine; 25H-NBOMe; 2-(2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine; 25I-NBOH; 2-(((4-iodo-2,5-dimethoxyphene

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2018 سفارش ترجمه

Synthesis and binding characteristics of [3H]neuromedin N, a NTS2 receptor ligand

Keywords: [35S] GTPγS; BH; Bolton-Hunter; Bmax; maximal number of the binding sites; BSA; bovine serum albumin; DIPEA; N,N-diisopropylethylamine; DMF; N,N-dimethylformamide; EC50; half maximal effective concentration; Emax; maximal stimulation (Efficacy); GDP; guanosine 5′-

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Substituted conformationally restricted guanidine derivatives: Probing the α2-adrenoceptors' binding pocket

Keywords: [35S] GTPγS; Conformationally restricted guanidines; 2-Amino-1,4-dihydroquinazolines; 2-Amino-1,4-dihydropyridopyrimidines; 2-Amino-4,5-dihydro-1,3-benzodiazepines; α2-adrenoceptors' ligands; α2-adrenoceptors' antagonists; Human brain tissue in vitro experiment

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

The histamine H4-receptor and the central and peripheral nervous system: A critical analysis of the literature

Keywords: [35S] GTPγS; Histamine H4 receptor; Nervous system; Neuron; Microglia; Antibody specificity; Publication bias; A 943931; H4R antagonist (4-((3R)-3-amino-pyrrolidin-1-yl)-6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-d]pyrimidin-2-ylamine); ACh; acetylcholine; AKT; protein k

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Design, synthesis, and pharmacological evaluation of JDTic analogs to examine the significance of replacement of the 3-hydroxyphenyl group with pyridine or thiophene bioisosteres

Keywords: [35S] GTPγS; [35S]GTPγS; sulfur-35 guanosine-5′-O-(3-thio)triphosphate; DAMGO; [D-Ala2,MePhe4,Gly-ol5]enkephalin; DPDPE; [D-Pen2,D-Pen5]enkephalin; U69,593; (5α,7α,8β)-(−)-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4,5]dec-8-yl]benzeneacetamide; JDTic; Opioids;

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2016 سفارش ترجمه

Synthesis and biological evaluation of indole-2-carboxamides bearing photoactivatable functionalities as novel allosteric modulators for the cannabinoid CB1 receptor

Keywords: [35S] GTPγS; Cannabinoid receptor; Allosteric modulator; Photoaffinity labeling; Photoactivatable ligands; CB1; Cannabinoid type 1 receptor; GPCR; G-protein coupled receptor; nAChRs; nicotinic acetylcholine receptors; BP; benzophenone; PTFMD; phenyltrifluoromethyldiaz

دانلود رایگان متن کامل مقاله ISI 56 صفحه سال انتشار : 2016 سفارش ترجمه

Regional differences in mu and kappa opioid receptor G-protein activation in brain in male and female prairie voles

Keywords: [35S] GTPγS; [35S]GTPγS; guanosine 5′-O[γ-35S] triphosphate; DAMGO; [d-Ala2,NMe-Phe4,Gly-ol5]-enkephalin; EGAT; ethylene glycol tetraacetic acid); NAc; nucleus accumbens; nor-BNI; nor-binaltorphimine; PBS; phosphate-buffered saline; second messenger; signaling; au

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Reelin influences the expression and function of dopamine D2 and serotonin 5-HT2A receptors: A comparative study

Keywords: [35S] GTPγS; ANOVA; analysis of variance; DOI; (±)-2,5-dimethoxy-4-iodoamphetamine; DTT; dl-dithiothreitol; EGTA; ethylene glycol tetraacetic acid; GDP; guanosine 5'-diphosphate; [35S]GTPγS; [35S]guanosine 5′-O-(gamma-thio)triphosphate; HEPES; 4-(2-hydroxyethyl)-1

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Investigation of the role of βarrestin2 in kappa opioid receptor modulation in a mouse model of pruritus

Keywords: [35S] GTPγS; Pruritus; Kappa opioid receptor; Biased ligand; Mouse models of itch; U50,488H; KOR antagonist; βarr2-KO; βarrestin2 knockout; CP; chloroquine phosphate; CPA; conditioned place aversion; DMSO; dimethyl sulfoxide; 5′-GNTI; 5′-guanidinonaltrindole; GP

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2015 سفارش ترجمه

Characterization of kappa opioid receptor mediated, dynorphin-stimulated [35S]GTPγS binding in mouse striatum for the evaluation of selective KOR ligands in an endogenous setting

Keywords: [35S] GTPγS; Dynorphin; Kappa opioid receptor; [35S]GTPγS binding; Mouse striatum; Selectivity; Drug discovery; KOR antagonist; CTOP; D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2; DAMGO; [D-Ala2, NMe-Phe4, Gly-ol5]-enkephalin; Dyn; dynorphin; DOR; delta opioid receptor; [

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2015 سفارش ترجمه

Repeated administration of phytocannabinoid Δ9-THC or synthetic cannabinoids JWH-018 and JWH-073 induces tolerance to hypothermia but not locomotor suppression in mice, and reduces CB1 receptor expression and function in a brain region-specific manner

Keywords: [35S] GTPγS; AM-2201; [1-(5-fluoropentyl)-1H-indol-3-yl]-1-naphthalenyl-methanone; CB1Rs; cannabinoid type 1 receptors; CP-47,497; rel-2-[(1S,3R)-3-hydroxycyclohexyl]-5-(2-methylnonan-2-yl)phenol; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclo

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2015 سفارش ترجمه

Allosteric modulators of human A2B adenosine receptor

Keywords: [35S] GTPγS; ADA; adenosine deaminase; AR; adenosine receptor; cAMP; 3′,5′-cyclic adenosine monophosphate; BAY 60-6583; 2-[6-amino-3,5-dicyano-4-[4-(cyclopropylmethoxy)phenyl]pyridin-2-ylsulfanyl]acetamide; CHO; Chinese hamster ovary; DMAP; 4-dimethylaminopyridine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Alterations of 5-HT1A receptor-induced G-protein functional activation and relationship to memory deficits in patients with pharmacoresistant temporal lobe epilepsy

Keywords: [35S] GTPγS; [35S]GTPγS; Neuropsi; Human tissue; Epilepsy; Serotonin; Memory;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Group II metabotropic glutamate receptor-mediated activation of G-proteins in rat hippocampal and striatal membranes

Keywords: [35S] GTPγS; CNS; central nervous system; NMDA; N-methyl-d-aspartate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; GPCR; G-protein-coupled receptor; mGlu receptor; metabotropic glutamate receptor; [35S]GTPγS; guanosine-5′-O-(3-[35S]thio)triphosphate

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen

Keywords: [35S] GTPγS; 4OH-Tam; 4OH-Tamoxifen; AC; adenylyl cyclase; CB1R; cannabinoid receptor type 1; CB2R; cannabinoid receptor type 2; CHO; Chinese hamster ovary; CP-55,940; 5-(1,1-dimethylheptyl)-2-[5-hydroxy-2-(3-hydroxypropyl)cyclohexyl]phenol; DMEM; Dulbecco's modific

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

[35S]GTPγS binding and opioid tolerance and efficacy in mouse spinal cord

Keywords: [35S] GTPγS; [35S]GTPγS; guanosine 5′-O-(3-[35S] thio)triphosphate; DAMGO; D-Ala2,N-MePhe4,Gly-ol5enkephalin; CCAM; clocinnamox; GRK; G-protein-coupled receptor kinase; cAMP; 3′-5′-cyclic adenosine monophosphate; PAG; periaqueductal gray; AAALAC; Association fo

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

The G protein-coupled cannabinoid-1 (CB1) receptor of mammalian brain: Inhibition by phthalate esters in vitro

Keywords: [35S] GTPγS; Brain cannabinoid-1 receptor; G-protein; Phthalates; [3H]CP-55940; [3H]SR141716A; [35S]GTPγS;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Up-regulation of adenylylcyclases I and II induced by long-term adaptation of rats to morphine fades away 20 days after morphine withdrawal

Keywords: [35S] GTPγS; AC; adenylyl cyclase; β-AR; β-adrenergic receptor; DADLE; [2-d-alanine, 5-d-leucine]enkephalin = Tyr-d-Ala-Gly-Phe-d-Leu; DAMGO; [2-d-alanine, 4-N-methylphenylalanine, 5-glycinol]enkephalin = Tyr-d-Ala-Gly-N-methyl-Phe-Gly-ol; DOR; δ-opioid recepto

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

A comprehensive study on the putative δ-opioid receptor (sub)types using the highly selective δ-antagonist, Tyr-Tic-(2S,3R)-β-MePhe-Phe-OH

Keywords: [35S] GTPγS; Bmax; receptor density; BNTX; 7-benzylidenenaltrexone; DADLE; [d-Ala2,d-Leu5]enkephalin; deltorphin II; Tyr-d-Ala-Phe-Glu-Val-Val-Gly-NH2; DOR-1; δ-opioid receptor; DOR-KO; δ-opioid receptor knock-out; DPDPE; Tyr-c[d-Pen-Gly-Phe-d-Pen]-OH; DSLET; Tyr-d-

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Europium-labeled GTP as a general nonradioactive substitute for [35S]GTPγS in high-throughput G protein studies

Keywords: [35S] GTPγS; G proteins; Eu-GTP; [35S]GTPγS; High throughput; Time-resolved fluorescence; G protein-coupled receptors;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease

Keywords: [35S] GTPγS; Ropinirole; Pramipexole; Pergolide; Antiparkinson; α2-Adrenoceptor; D2 receptor; D3 receptor; ACh; acetylcholine; Akt; atypical kinase; AR; adrenoceptor; BDNF; brain derived neurotrophic factor; COMT; catechol-Ortho-methyltransferase; DA; dopamine; ERK;

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2010 سفارش ترجمه

Modification of the furan ring of salvinorin A: Identification of a selective partial agonist at the kappa opioid receptor

Keywords: [35S] GTPγS; Kappa opioid receptor agonists; Salvinorin; Binding; [35S]GTPγS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Biochemical anti-opioid action of NPFF2 receptors in rat spinal cord

Keywords: [35S] GTPγS; NPFF; Opioid; Receptor; Anti-opioid; [35S]GTPγS;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Endogenous heptapeptide Met-enkephalin-Gly-Tyr binds differentially to duplicate delta opioid receptors from zebrafish

Keywords: [35S] GTPγS; Met-enkephalin-Gly-Tyr; Peptide analogues; Delta opioid receptor; Radioligand binding; [35S]GTPγS; Zebrafish;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Effects of central galanin administration on muscarinic cholinergic and galanin receptor G protein coupling

Keywords: [35S] GTPγS; Galanin; Cholinergic; Muscarinic; G-protein; [35S]GTPγS; Autoradiography; Neurotrophic; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Effects of long-term biogenic amine transporter blockade on receptor/G-protein coupling in rat brain

Keywords: [35S] GTPγS; Tropane; [35S]GTPγS; Monoamine transporters; Dopamine D2 receptors; 5-HT1A receptors; α2-Adrenergic receptors;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Mechanisms of mu opioid receptor/G-protein desensitization in brain by chronic heroin administration

Keywords: [35S] GTPγS; Mu opioid; G-protein; Heroin; [35S]GTPγS; Desensitization;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2005 سفارش ترجمه